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Duke Medical Imaging Technology Fair

Tayyaba Hasan

Wednesday, February 27, 2019

2019 Medical Imaging Technology Fair

Tayyaba Hasan, Ph.D. Professor of Dermatology, Harvard Medical School

3:00 pm | Bryan Research 103

MITP Poster Session and Reception

4:15 pm – 6:00 pm | Fitzpatrick Center (FCIEMAS) Prefunction Area

Integrating Molecular Imaging with Spatiotemporally Synchronized Cancer Combinatorial Therapy using Photo-Activatable Nanoconstruct Platforms

Abstract: Optical activation of materials leads to thermal, photochemical and radioactive processes. These processes can be captured for imaging and response-based therapeutic design. The ability to use light as a reagent allows for spatiotemporal control of molecular release when multiagents are encapsulated in appropriate nanoconstructs. This enables simultaneous imaging and therapeutics. With recent advances technological advances, light-based treatments and imaging can also be adapted for application to Low to Middle Income Countries (LMICS). Strategies for optimizing the impact of light-based therapeutics will be discussed.

Biography: Tayyaba Hasan, PhD, is a Professor of Dermatology at Harvard Medical School (HMS) and a Professor of Health Sciences and Technology (Harvard-MIT). The focus of her research is in photochemical approaches to treatment and diagnosis of disease primarily in the areas of cancer and infections. She has over 249 publications and 23 inventions from research funded by the National Institutes of Health (NIH), the Department of Defense and Industry grants. Dr. Hasan leads a NCI funded multinational Program Project grant focused on image-guided treatment of pancreatic and skin cancers and an International consortium on developing low cost enabling technologies for image-guided photodynamic therapy of oral cancer. Dr. Hasan is an inventor of the FDA approved photodynamic treatment of Age-Related Macular Degeneration and several other applications in fields of cancer, infections and technology. In recognition for her contribution to translational work and other discoveries she was the recipient of the NIH Pioneer Award in Biomedical Optics, Bench to Bedside Translation and was featured in a Special Section Honoring Pioneers in Biomedical Optics in the Journal of Biomedical Optics September/October 2010 issue. She received the Lifetime Achievement Award in recognition for sustained innovation and contribution in year 2015 and the significant advancement of photodynamic therapy award in 2017 for research excellence in the field of photodynamic therapy from the International Photodynamic Association. She was awarded the Britton Chance Biomedical Optics Award in recognition of trailblazing contributions to the field of Photodynamic Therapy and its clinical translation, leadership and service to the photonics community at the SPIE Photonics West meeting in 2018, and the Society of American Asian Scientists in Cancer Research (SAASCR) award for her outstanding scientific contributions in the field of cancer research at the Annual American Association of Cancer Research meeting in Chicago in 2018. She was also awarded the Lifetime Achievement Award which recognizes the illustrious career of a senior researcher whose work has significantly advanced the research areas of the American Society for Photobiology (ASP), at the ASP Biennial meeting in May 2018. Dr. Hasan was elected to the National Academy of Inventors (NAI) as a Fellow in December 2018 and will be formally inducted by United State Commissioner for Patents in the National Academy of Inventors at the 2019 NAI Fellows Induction Ceremony at the Space Center Houston.

Dr. Hasan has several leadership roles in national and international organizations. She was the President of the American Society for Photobiology (2010-2012), and is the current President of the International Photodynamic Association and has served as the Vice President of Science for the Pan American Photodynamic Therapy Association. She serves on several advisory boards of academic and non-academic organizations. Dr. Hasan is a member of the editorial board of national and international journals and has served as conference chair, sub-section and session chair at national and international conferences.

Dr. Hasan has had a long-term involvement in helping the career development of junior scientists and helped found the Office for Research Career Development (ORCD) at Massachusetts General Hospital (MGH) where she also served as its first Director until 2011. The Posters of Excellence awards at the MGH Office for Research Career Development’s (ORCD) Research Fellow Poster Celebration were named “The Tayyaba Hasan ORCD Posters of Prestige” given annually to honor Dr. Hasan’s contributions as the founding director. Her commitment to teaching and training has earned her the William Silen Lifetime Achievement in Mentoring Award from Harvard Medical School. She is also the recipient of the National Postdoctoral Mentor Award, the Tenth Anniversary Mentor Award, from the National Postdoctoral Association. Dr. Hasan was recognized for her dedication to equity in Science, Engineering and Technology and was the Catalyst Award Honoree from the Science Club for Girls in Cambridge, Massachusetts an outreach organization dedicated to encouraging girls from underprivileged background to pursue careers in science and medicine (2010).