Medical Imaging Training at Duke University

Duke Imaging Technology Fairs

The 2017-2018 Imaging Technology Fair is coming soon! 

January 11, 2018

Visionary Speaker:  Matthew O’Donnell, Ph.D., University of Washington

 

What Will it Take for Photoacoustic Imaging to be Used Routinely in the Clinic?

Abstract: With recent developments in molecular-scale bioconjugated contrast agents and integrated system design, photoacoustics (PA) is rapidly bringing molecular sensitivity to ultrasound (US) imaging for many biomedical applications. The same agents can potentially be used for molecularly-targeted therapies as well, opening the possibility for molecular theranostics using integrated photoacoustics/ultrasonics (PAUS). In this presentation, we will explore a class of nanoemulsion-based contrast agents that can potentially be used for photoacoustic imaging, ultrasonic imaging, and molecularly-targeted therapies combining light/ultrasound excitation. In particular, excitation techniques have been developed exploiting the non-linear characteristics of the nanoemulsions to provide both high sensitivity and specificity for molecular imaging and therapy. Finally, a system capable of integrated PAUS imaging at real-time frame rates will be presented that can monitor molecular theranostic procedures enabled by these nanoemulsions.

Biography: Dr. O’Donnell is renowned for his interdisciplinary focus, including research work in the field of ultrasound at institutions such as the University of Notre Dame, the University of Michigan and currently, as Dean Emeritus of engineering at The University of Washington.  As an expert in ultrasound imaging, his research has resulted in more than 300 publications and numerous awards including the Achievement Award from the IEEE-UFFC Society and membership to the National Academy of Engineering.  Previously, Dr. O’Donnell served as part of General Electric’s corporate research team at their research and development center.

___________________________________

Congratulations to the winners of the 2016 Imaging Technology Fair

 November 16, 2016   3pm - 6pm  

CIEMAS Schiciano auditiorium & lobby

Visionary Seminar Speaker:  Kim Butts Pauly, Ph.D., Stanford University

MRI-guided Focused Ultrasound: Ablation to BBB opening to Neuromodulation

Abstract: Using a large area transducer, ultrasound can be focused deep into the body without any damage to intervening tissue. In ablative applications in the brain, MRI is used for targeting and for monitoring tissue temperature. It is important to assess that an effective temperature rise is achieved at the target, without heating nearby tissue. I will describe our MR thermometry methods that are robust to patient motion. Another important application of focused ultrasound is opening the blood-brain barrier for the delivery of therapeutics, such as chemotherapy and antibodies. In ultrasound-based neuromodulation, the brain is directly stimulated, eliciting behavior such as limb twitches in rodents. For both these applications, I will describe our work to calibrate the beam pressure with patient-specific CT-based simulation and MR acoustic radiation force imaging.

Biography: Kim Butts Pauly obtained a B.S. in Physics from Duke University. She received a Ph.D. from the Mayo Graduate School where she studied diagnostic MRI physics.  After a short postdoc at Stanford, she joined the faculty in the Department of Radiology at Stanford in 1996. Her work is currently focused on MRI-guided focused ultrasound in applications ranging from cancer treatment to functional disorders. She currently has courtesy appointments in both Biomedical Engineering and Electrical Engineering and is division chief for the Radiological Sciences Laboratory within Radiology.

The Imaging Technology fair will also include a poster session followed by a reception.

Sponsored by the Biomedical Engineering Medical Imaging Training Program and the Center for In Vivo Microscopy.